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Bactrim, also known as a Sulfonamide and Trimethoprim combination, is used to prevent and treat infections. In children, the most common uses are for ear infections and urinary tract infections. It also has a role in the treatment of chronic bronchitis, traveler's diarrhea, shigella, and in both the treatment and prevention of pneumocystis carinii pneumonia.

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About Sulfonamide and Trimethoprim

Most bacteria must manufacture their own supply of folic acid or folate. Some bacteria depend on outside sources of folic acid, getting what they need from what they eat. Trimethoprim and sulfamethoxazole are both compounds that block the internal production of folic acid. Thus these compounds are relatively safe for humans, yet lethal to many bacteria. The combination product, Bactrim (other brand names: Septra, Cotrim) is far more effective than either ingredient alone.

Bactrim usage

Bactrim should be used as long as it is indicated for one or another infection. Do exceed the dosage or decrease it on your own. Some individuals may develop allergy to Bactrim or its generic - sulfamethoxazole or trimethoprim. Such patients should not use it in this case. It is important that you drink plenty of fluids while taking this medication in order to prevent sediment in the urine and the formation of stones.Bactrim works best when there is a constant amount in the blood. It is best to take doses at evenly spaced times day and night.

Special warning about Bactrim

Make sure your doctor knows if you have impaired kidney or liver function, have a folic acid deficiency, are a chronic alcoholic, are taking anticonvulsants, have been diagnosed as having abnormal intestinal absorption, are in a state of poor nutrition, or have severe allergies or bronchial asthma. If Bactrim is taken with certain other drugs, the effects of either could be increased, decreased, or altered.

Bactrim side effects

Tell your doctor right away if you have: abdominal pain or tenderness; anxiety; blood in urine; bluish fingernails, lips, or skin; confusion; diarrhea; difficulty breathing; drowsiness; fever; general feeling of illness; greatly increased or decreased frequency of urination or amount of urine; hallucinations; increased thirst; lower back pain; depression; muscle pain or weakness; nausea; nervousness; pain or burning while urinating; seizures; stiff neck and/or back; or swelling of the front part of neck.

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